Nanotechnology presents A selection of chances to contribute to biology. In this article I will existing illustrations where by nanofabrication – the opportunity to make confined structures with Proportions at will – is applied to examine the biophysics of one molecules and cells. I will present some illustrations from our lab:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
For a individual, I hold the biblical assignment to investigate and use everything in creation for the good thing about my neighbour. I will not experience any conflict in between faith and science. Quite the opposite, my religion stimulates me to perform science, for being open-minded on this planet.’
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on one molecules and steel clusters
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
SMC complexes can go physical roadblocks bigger than their ring sizing, indicating a nontopological system for DNA loop extrusion
Many linked developments followed, where our team founded different transistor variants for instance solitary-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying https://www.ceesdekker.net diodes, and coupled many transistors into compact evidence-of-basic principle Digital circuits.
Studying DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
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Bulk-surface coupling identifies the mechanistic relationship in between Min-protein designs in vivo As well as in vitro
‘The concept that You can find such a point for a commencing, a big bang, is currently a fascinating signpost to contemplate that there was a creator. But far more frequently, and on The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is really a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.
2006, initial demonstration of molecular sorting in a lab on the chip working with biomotors; discovery of nanobubbles in good-point out nanopores; and initial estimate of electrokinetic Strength conversion inside of a nanofluidic channel
Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy procedures
Illustration (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in crimson, and also a 3D rendering in the movement from the DNA rod is shown.